Proviron (Mesterolone) is not an aromatizing steroid so doesn’t come
with estrogenic side effects. More than that, it does have the ability
to affect the aromatase enzyme in a way that can actually bind to it and
inhibit its activity, giving Proviron some measure of aromatase
inhibition or anti-estrogen effect.
While this isn’t anywhere near as powerful as a true aromatase inhibitor, it is a welcome attribute of a steroid when so many other steroids display the very opposite effects. However while estrogen related side effects aren’t an issue with Proviron itself, there are other potential side effects to be aware of.
Androgenic side effects: Mesterolone has some strong androgenic effects, after all it was originally made to medically treat deficiencies in androgen. It is based on DHT which itself is an androgen so it should come as no surprise that you can expect to see activity in this area and these side effects cover issues that most steroid users will be familiar with, including potential acne and hair loss or male pattern baldness.
The occurrence and severity of these particular side effects are highly individual and some people may experience very little or none at all, while others will see quite severe flare ups of acne. When it comes to hair loss, if you’re genetically predisposed to baldness then Proviron can stimulate this to happen much earlier than it might otherwise have done so. Guys without any genetic links to hair loss won’t have to worry about this androgenic side effect.
The high androgenic activity in Mesterolone makes it unsuitable for use by females as it’s almost certain to cause an onset of masculine features like a deeper voice and body hair growth. Mesterolone is an even higher risk for females when it comes to these side effects compared with some other steroids and therefore Proviron is not recommended to be used by females.
Another area that raises concerns with Proviron use is that of cholesterol and compared with many other steroids which themselves can cause some serious impacts on cholesterol, Proviron is considered one of the more harsh ones in this regard and one that comes with high risk to cholesterol health.
For this reason anyone with existing high cholesterol issues is always advised to avoid using Proviron at all. Even those with normal cholesterol levels will need to remain alert to what effect Proviron is having on your cholesterol throughout your cycle.
There’s no doubt that Mesterolone can have very strong impact on your good cholesterol levels, potentially reducing them by almost a third in some cases. At the same time it can be raising your bad cholesterol levels by a significant amount.
Without sustained cholesterol friendly diet habits and cardio exercise while you’re using Proviron, it does pose a very high risk in this area so anyone wanting to use Proviron absolutely must formulate a plan to help maintain healthy cholesterol for the duration of the cycle.
As you might expect, Mesterolone also comes with the side effect of testosterone suppression but its impact is quite minimal when compared to almost any other steroid. At the dose that most guys will be using Proviron it is unlikely to cause any noticeable testosterone suppression related side effects and therefore it is one of the very few steroids you can use in most cases without the need for adding a testosterone steroid.