Dermorphin

Dermorphin

Dermorphin is about 30–40 times more potent than morphine but theoretically may be less likely to produce drug tolerance and addiction. The amino acid sequence of dermorphin is H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2.
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Product Details

Description

Dermorphin is a hepta-peptide first isolated from the skin of South American frogs belonging to the genus Phyllomedusa. The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors.


Usage

Dermorphin has been illegally used in horse racing as a performance-enhancing drug. Due to dermorphin's painkilling activity, horses treated with dermorphin may run harder than they would otherwise.

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Specification

Identity by HPLC

The retention is same with the reference substance

Appearance

White powder or almost white powder

Sequence

Glu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHC2H5

PUrity (By HPLC)

≥98.0%

Related Substance (By HPLC)

Total Impurities(%)≤2.0%

Largest Single Impurity(%)

≤1.0%

Acetate Content (By HPLC)

≤12.0%

Water Content(Karl Fischer)

≤8.0%

Bacterial Endotoxins

≤ 70 IU/mg


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